Invited Review Articles
Oxidize me to the space.
Yang J
Nat Chem Biol. 2022, 18(7): 680–681, Link
Sweetly profiling the cysteinome.
Yang J
Nat Chem Biol. 2019, 15(10): 935-936 Link
Mapping the cysteine redoxome: advances and prospects (in Chinese)
Yang J
*Corresponding author, †Co-first author
Nucleophilic covalent ligand discovery for the cysteine redoxome.
Fu L†, Jung Y†, Tian C, Ferreira R, Cheng R, He F, Yang J*, Carroll KS*.
Nat Chem Biol, 2023, 19(11): 1309-1319 Link (Featured by NCB's News & Views)
A modification-centric assessment tool for the performance of chemoproteomic probes.
He J†, Fei Z†, Fu L, Tian C, He F, Chi H*, Yang J*.
Nat Chem Biol, 2022, 18(8): 904-912 Link (Featured by NCB's News & Views)
Wittig reagents for chemoselective sulfenic acid ligation enables global site stoichiometry analysis and redox-controlled mitochondrial targeting.
Shi Y , Fu L, Yang J*, Carroll KS*.
Nat Chem, 2021, 13: 1140-1150. Link (Highlighted by Nat Chem Biol)
Bi G † , Hu M † , Fu L † , Zhang X, Zuo J, Li J, Yang J* , Zhou JM*.
Nat Plants, 2022, 8(10): 1160-1175. Link (Featured by Nat Plants' News & Views)
Global profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans.
Meng J†
, Fu L†, Liu K, Tian C, Wu Z, Jung Y, Ferreira R, Carroll KS, Blackwell TK*, Yang J*.
Nat Commun, 2021, 12: 1415. Link
A quantitative thiol reactivity profiling platform to analyze redox and electrophile reactive cysteine proteomes.
Fu L†, Li Z†, Tian C†, Liu K†, He JX, He JY, He F, Xu P, Yang J*.
Nat Protoc, 2020, 15(9): 2891-2919. Link
Direct proteomic mapping of cysteine persulfidation.
Fu L†, Liu K†, He J, Tian C, Yu X, Yang J*.
Antioxid Redox Signal. 2020, 33(15): 1061-1076 Link
Chemical Proteomics Reveals New Targets of Cysteine Sulfinic Acid Reductase.
Akter S†, Fu L†, Jung Y, Lo Conte M, Lawson JR, Lowther TW, Sun R, Liu K, Yang J*, Carroll KS*.
Nat Chem Biol. 2018, 14 (11): 995-1004 Link (Featured by NCB's News & Views & Nat Methods's Research Highlights In Brief)
Multiplexed Thiol Reactivity Profiling for Target Discovery of Electrophilic Natural Products.
Tian C, Fu L, Liu K, Sun R, Yang Y, Yang J*.
Cell Chem Biol, 2017, 24(11):1416-1427 Link
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Sun R†, Fu L†, Liu K, Tian C, Yang Y, Tallman KA, Porter NA, Liebler DC, Yang J*.
Mol Cell Proteomics, 2017, 16:1789-1800 (Editors'
Highlight)
Link
Systematic and quantitative assessment of hydrogen peroxide reactivity with cysteines across human proteomes.
Fu L†, Liu K†, Sun M, Sun R, Tian C, Bentanzos C, Tallman KA, Porter NA, Yang Y, Guo D, Liebler DC, Yang J*.
Mol Cell Proteomics, 2017, 16:1815-1828 Link
Other Research Articles
Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics.
Li Z †, Liu K †, Xu P, Yang J*.
J Proteome Res. 2022, 21: 1349–1358 Link
Dóka E, Arnér ESJ, Schmidt EE, Dick TP, van der Vliet A, Yang J, Szatmári R, Ditrói T, Wallace JL, Cirino G, Olson K, Motohashi H, Fukuto JM, Pluth MD, Feelisch M, Akaike T, Wink DA, Ignarro LJ, Péter Nagy*.
Sci Adv, 2021, 7(17): eabe7006 Link
Hydrogen Sulfide-linked Persulfidation of ABSCISIC INSENSITIVE 4 Controls Arabidopsis ABA Responses Through the Transactivation of Mitogen-Activated Protein Kinase Kinase Kinase 18.
Zhou M, Zhang J, Shen J, Zhou H, Zhao D, Gotor C, Romero LC, Fu L, Li Z, Yang J, Shen W, Yuan X, Xie Y*.
Mol Plant, 2021, S1674-2052(21): 00082-4 Link
Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling.
Huang Y, Li Z, Zhang L, Tang H, Zhang H, Wang C, Chen S, Bu D, Zhang Z, Zhu Z, Yuan P, Li K, Yu X, Kong W, Tang C, Jung Y, Ferreira R, Carroll KS, Du J, Yang J*, Jin H*.
Redox Biol, 2021, 41: 101898. Link
Structures of the glucocorticoid-bound adhesion receptor GPR97-Go complex.
Ping YQ†, Mao C†, Xiao P†, Zhao RJ†, Jiang Y†, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao XN, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE*, Zhang Y*, Sun JP*.
Nature, 2021, 589: 620-626. Link
An Arabidopsis Secondary Metabolite Directly Targets Expression of the Bacterial Type III Secretion System to Inhibit Bacterial Virulence.
Wang W†, Yang J†, Zhang J, Liu Y, Tian C, Qu B, Gao C, Xin P, Chen S, Zhang W, Miao P, Li L, Zhang X, Chu J, Zuo J, Li J, Bai Y, Lei X*, Zhou J*.
Cell Host Microbe. 2020, 27(4): 601-613. Link
A clickable APEX probe for proximity-dependent proteomic profiling in yeast.
Li Y, Tian C, Liu K, Zhou Y, Yang J*, Zou P*.
Cell Chem Biol. 2020, 27(7): 858-865. Link
Persulfidation-based modification of cysteine desulfhydrase and the NADPH oxidase RBOHD controls guard cell abscisic acid signaling.
Shen J†, Zhang J†, Zhou M†, Zhou H†, Cui B, Gotor C, Romero LC, Fu L, Yang J, Foyer CH, Pan Q, Shen W, Xie Y*.
Plant Cell. 2020, 32(4):1000-1017 Link
Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites.
Huang J † , Willems P † , Wei B † , Tian C, Ferreira R, Bodra N, Gache S, Wahni K, Liu K, Vertommen D, Gevaert K, Carroll KS, Van Montagu M*, Yang J*, Van Breusegem F*, Messens J*.
Proc Natl Acad Sci U S A, 2019, 116 (42): 21256-21261. Link
Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks.
Pei J, Li X, Li W, Gao Q, Zhang Y, Wang X, Fu J, Cui S, Qu J, Zhao X, Hao D, Ju D, Liu N, Carroll KS, Yang J, Zhang EE, Cao J, Chen H*, Liu D*.
Nat Cell Biol. 2019, 21(12): 1553-1564 Link
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair.
Yang W†, Tao Y†, Wu Y, Zhao X, Ye W, Zhao D, Fu L, Tian C, Yang J, He F*, Tang L*.
Nat Commun. 2019, 10(1): 1076 Link
Proteome‐Wide Analysis of Cysteine S‐Sulfenylation Using a Benzothiazine‐Based Probe.
Fu L†, Liu K† , Ferreira RB, Carroll KS, Yang J*.
Curr Protoc Protein Sci. 2019, 95(1): e76 Link
Dynamic Redox Balance Directs the Oocyte-to-Embryo Transition via Developmentally Controlled Reactive Cysteine Changes.
Petrova B, Liu K, Tian C, Kitaoka M, Freinkman E, Yang J*, Orr-Weaver TL*.
Proc Natl Acad Sci U S A. 2018, 115 (34): E7978-E7986 Link
Chemoproteomics Reveals Unexpected Lysine/Arginine-Specific Cleavage of Peptide Chains as a Potential Protein Degradation Machinery.
Tian C, Liu K, Sun R, Fu L, Yang J*.
Anal Chem. 2018, 90: 794-800 Link
A chemoproteomic platform to assess bioactivation potential of drugs.
Sun R, Shi F, Liu K, Fu L, Tian C, Yang Y, Tallman KA, Porter NA, Yang J*.
Chem Res Toxicol. 2017, 30: 1797-1803 Link
Selected publications pre-independence (2007-2015)
*Corresponding author, †Co-first author
The expanding landscape of the thiol proteome.
Yang J*, Carroll KS, Liebler DC*.
Mol Cell Proteomics, 2016, 15: 1-11 Link
Yang J, Gupta V, Carroll KS, Liebler DC*.
Nat Commun. 2014, 5: 4776 Link
Yang J*, Gupta V, Tallman KA, Porter NA, Carroll KS, Liebler DC*.
Nat Protoc. 2015, 10: 1022-37 Link
Gupta V†, Yang J†, Liebler DC, Carroll KS*.
J Am Chem Soc, 2017, 139: 5588−5595 (Highlighted in C&E News) Link
Quantitative chemoproteomics for site-specific analysis of protein alkylation by 4-hydroxy-2-nonenal in cells.
Yang J, Tallman KA, Porter NA, Liebler DC*.
Anal Chem. 2015, 87: 2535-41 (Editors' Highlight) Link
Gambogic acid deactivates cytosolic and mitochondrial thioredoxins by covalent binding the functional domain.
Yang J † , Li C † , Ding L*, Guo Q, You Q, Jin S.
J Nat Prod. 2012, 75: 1108-1116 Link
Yang J, Ding L*, Hu L, Qian W, Jin S, Sun X, Wang Z, Xiao W.
Drug Metab Dispos. 2011, 39: 617-26 Link
Retrieving tweets.