Jing Yang, Ph.D.
Principal Investigator 

Jing, originally from Changsha, a city in the southern central region of China, earned his PhD from China Pharmaceutical University in 2012. Following that, he served as a postdoctoral fellow at Vanderbilt University from 2012 to 2015. In 2015, he was recruited as a Principal Investigator at the National Center for Protein Sciences • Beijing, with a joint appointment at the State Key Laboratory of Proteomics and Beijing Proteome Research Center.

In the spring of 2023, he joined the Guangzhou National Laboratory. The Yang lab, under his leadership, is dedicated to advancing chemical proteomic technologies, addressing fundamental questions in redox biology, and exploring the "druggable" space of the cysteine redox proteome.

As the corresponding author, Jing has published 25 research papers in numerous high-profile journals. Several of these works have been featured by Nature Research Journals in News & Views or Research/Cover Highlights. Recognized for his contributions, he was selected as one of JPR (Journal of Proteome Research)'s 40 Under 40 in 2021 and joined the Editorial Advisory Board in 2022.

Currently, he serves as the Chair of the 3rd ECR Council of CNHUPO (China Human Proteome Organization). Jing has received invitations to speak at numerous prestigious academic conferences, including the Gordon Research Conference, EMBL Conference, EMBO Workshop, Keystone Symposia, and others.

Members @Yanglab_GZlab

Jingwen Chen

Lab manager @Yanglab_GZlab

Jiawei Mao, Ph.D.

Associate Investigator @Yanglab_GZlab

Jiawei earned his Ph.D. in Analytical Chemistry under the guidance of Prof. Mingliang Ye at the Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Following a 2-year postdoc training at the Southern University of Science and Technology, he became a member of my lab in 2023. Jiawei's research focuses on computational proteomics, machine learning, and data visualization. In his leisure time, he finds enjoyment in reading, swimming, and hiking.

Junfeng Huang, Ph.D.

Associate Investigator @Yanglab_GZlab

Junfeng Huang, received his Ph.D. in Analytical Chemistry under the guidance of Prof. Mingliang Ye at Dalian Institute of Chemical Physics, Chinese Academy of Sciences. He had developed a series of new enrichment methods and technologies for the large-scale analyses of protein post-translational modifications especially ubiquitylation, phosphorylation, glycosylation, mannose-6-phosphate (M6P) glycosylation and histone methylation in complex biological samples. He has published 27 peer-reviewed papers and 10 first-author papers in journals of Analytical Chemistry, Journal of Proteome Research, ACS Applied Materials and Interfaces and so on, which have been cited more than 900 times.

Yi Zhang

Software Engineer @Yanglab_GZlab

Yi earned his master's degree in Biology and Medicine from South China University of Technology in July 2023. He brings extensive expertise in graph neural networks, geometric deep learning, and generative models. Devoted to advancing innovative AI solutions for real-world challenges, Yi focuses particularly on applications in proteomics and drug discovery. Currently, he is exploring new frontiers for AI in probe discovery.

Wenfeng Wu

PhD student @Yanglab_GZlab

Wenfeng Wu earned a bachelor's degree in pharmaceutical engineering from Tianjin University in 2017. Subsequently, he completed a master's degree in developmental biology at Southwest University in 2020. Following this, Wenfeng joined the Guangzhou Institutes of Biomedicine and Health (CAS) as a research assistant, primarily specializing in protein mass spectrometry.

In 2023, Wenfeng Wu became a Ph.D. student (Joint Student with Guangzhou Medical University) upon joining Yang's lab, pursuing his research aspirations. On a personal note, cooking food is one of his favorite pastimes.

Lu Sun

PhD student @Yanglab_GZlab

Sun Lu studied Applied Chemistry at Beijing University of Chemical Technology (BUCT) and earned his Diploma in Applied Chemistry in 2018. He furthered his academic pursuits by obtaining a Master's degree in Organic Chemistry from Beijing University of Chemical Technology in 2021. Post-graduation, Sun Lu gained valuable experience working in drug synthesis and organic synthesis at Simcere Pharmaceutical Co., Ltd.

In 2023, Sun Lu embarked on his doctoral studies by joining the research group led by Yang Jing at Guangzhou National Laboratory and Guangzhou Medical University, where he is enrolled as a joint student.

Haiyan Hu 

Lab manager @Yanglab_NCPSB

Ling Fu, Ph.D.

Co-PI @Yanglab_NCPSB

Ling received her Ph.D. in Microbiology at Shanghai Jiaotong University under the guidance of Prof. Jun Xu. She joined my Lab as a postdoc in 2016. Since then, she has been working on mapping protein S-sulfenylation (-SOH) and S-sulfinylation (-SO2H) in various model organisms using state-of-the-art chemoproteomic technology. Outside the Lab, she enjoys a couple of things, including reading and photography. Her favorite pop singers include Jay Chou, Wei Xu, Taylor Swift and Maroon 5. She also likes to play badminton and basketball in her free time. BTW, She idolizes Kobe Bryant!

Keke Liu, Ph.D.

Assistant Investigator @Yanglab_NCPSB

Keke obtained my Ph.D. in Microbiology, mentored by Prof.  Xingzhong Liu, at Institute of Microbiology, Chinese Academy of Sciences. He joined my Lab in 2016 after he finished a 2-year postdoc training in the brewery industry. He is interested in bioinformatics, the so-called 'dry' experiment, as compared with 'wet' experiments. He helps us to establish several informatics workflows, which greatly facilitates our capability for processing site-centric chemoproteomic data. In addition, he provides various bioinformatics solutions for the projects done or being done in my group. 

Caiping Tian

PhD Student (Joint program with Tsinghua University)  @Yanglab_NCPSB

Caiping obtained the M.S. in Biotechnology at China Pharmaceutical University. Her adviser is Prof. Yueqing Gu. After graduation, she became the first member in my Lab, helping me set up the Lab. Her research in my Lab is focused on target identification of synthetic and naturally occurring electrophiles. She also help us identify a novel endogenous protein electrophilie, N-formyl protein degradants. Outside the Lab, she likes mountain climbing. As her quote from an ancient poetry, "Reaching the top, then you can hold all mountains in a single glance". 

Jingyang He, M.S.

PhD Student (Joint program with Tsinghua University)  @Yanglab_NCPSB

Jixiang He

Technician  @Yanglab_NCPSB

Minran was born in Langfang, Hebei, which is known as the Beijing-Tianjin corridor. He obtained a bachelor's degree in applied chemistry from Fujian Agriculture and Forestry University in 2017. Subsequently, under the guidance of Associate Professor Jiangjiang Tang, he obtained a master's degree in chemical biology from Northwest A&F University in 2020. Thereafter, he joint our team. In his spare time, he likes to play Genting Game and traditional sports, including basketball, badminton and swimming. He's a fan of the San Antonio Spurs and Spurs legend Tim Duncan.

Former Members

Ruifeng Cheng

Previous position: graduate student from the joint program of NCPSB-Anhui Medical College 2020-2023 

Current position: Technician @ CRO 

Previous position: graduate student from the joint program of NCPSB-Anhui Medical College 2019-2022

Current position: Ph.D. student at Jin's lab at the Peking University First Hospital, Beijing

Rui Sun, M.S.

Previous position: Visiting graduate student from China Pharmaceutical University 2015-2017

Current position: Ph.D. student at Guo's lab at the Westlake University, Hangzhou